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Relapsing and Remitting Human Immunodeficiency Virus-Associated Leukoencephalomyelopathy Ann Neurol 31:34-38, Berger,J.R.,et al, 1992 See this aricle in Pubmed Article Abstract We describe a 33-year-old homosexual man with a steroid-responsive, remitting and relapsing leukoencephalopathy associated with recent human immunodeficiency virus type 1(HIV-1)seroconversion.Biopsy of a parieto- occipital lesion revealed demyelination and astrogliosis with focal necrosis.Detailed investigations demonstrated no pathogens in the brain other than HIV-1.This patient illustrates that a neurological disorder clinically indistinguishable from multiple sclerosis may be the presenting manifestation of HIV-1 infection and may occur in the absence of clinically significant immunosuppression.

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(click to filter results - removes previous filter) demyelinating disease human immunodeficiency virus type 1 leukoencephalopathy MRI MRI,abnormal multiple sclerosis multiple sclerosis,differential diagnosis of myelitis,transverse myelopathy optic neuritis

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